Cerebrospinal Fluid Biomarkers, Education, Brain Volume and Future Cognition

OBJECTIVE: To evaluate the combination of cerebrospinal fluid biomarkers of Aβ(42), tau, and phosphorylated tau (ptau(181)) with education and normalized whole brain volume (nWBV) to predict incident cognitive impairment and test the cognitive/brain reserve hypothesis. DESIGN: Longitudinal cohort st...

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Hoofdauteurs: Roe, Catherine M., Fagan, Anne M., Grant, Elizabeth A., Marcus, Daniel S., Benzinger, Tammie L. S., Mintun, Mark A., Holtzman, David. M., Morris, John C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203689/
https://ncbi.nlm.nih.gov/pubmed/21911695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2011.192
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