Cerebrospinal Fluid Biomarkers, Education, Brain Volume and Future Cognition

OBJECTIVE: To evaluate the combination of cerebrospinal fluid biomarkers of Aβ(42), tau, and phosphorylated tau (ptau(181)) with education and normalized whole brain volume (nWBV) to predict incident cognitive impairment and test the cognitive/brain reserve hypothesis. DESIGN: Longitudinal cohort st...

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Autors principals: Roe, Catherine M., Fagan, Anne M., Grant, Elizabeth A., Marcus, Daniel S., Benzinger, Tammie L. S., Mintun, Mark A., Holtzman, David. M., Morris, John C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203689/
https://ncbi.nlm.nih.gov/pubmed/21911695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archneurol.2011.192
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