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Nickel-Catalyzed Cycloisomerization of Enynes: Catalyst Generation via C-H Activation of Carbene Ligands

The combination of Ni(0) and an N-heterocyclic carbene act as a precatalyst for the cycloisomerization of enynes to afford 1,3-dienes. During the course of the reaction, a nickel hydride is formed from oxidative addition of the ortho C-H on the carbene ligand. Deuteriumn labeling studies are present...

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Detalhes bibliográficos
Main Authors: Tekavec, Thomas N., Louie, Janis
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203641/
https://ncbi.nlm.nih.gov/pubmed/22039310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2008.03.071
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