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Efficient internal exon recognition depends on near equal contributions from the 3′ and 5′ splice sites

Pre-mRNA splicing is carried out by the spliceosome, which identifies exons and removes intervening introns. In vertebrates, most splice sites are initially recognized by the spliceosome across the exon, because most exons are small and surrounded by large introns. This gene architecture predicts th...

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Detalles Bibliográficos
Main Authors: Shepard, Peter J., Choi, Eun-A., Busch, Anke, Hertel, Klemens J.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
RNA
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203598/
https://ncbi.nlm.nih.gov/pubmed/21795381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr481
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