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Targeted isolation of cloned genomic regions by recombineering for haplotype phasing and isogenic targeting

Studying genetic variations in the human genome is important for understanding phenotypes and complex traits, including rare personal variations and their associations with disease. The interpretation of polymorphisms requires reliable methods to isolate natural genetic variations, including combina...

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Main Authors: Nedelkova, Marta, Maresca, Marcello, Fu, Jun, Rostovskaya, Maria, Chenna, Ramu, Thiede, Christian, Anastassiadis, Konstantinos, Sarov, Mihail, Stewart, A. Francis
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203589/
https://ncbi.nlm.nih.gov/pubmed/21852329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr668
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