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Reduced secretion of structurally abnormal type I procollagen in a form of osteogenesis imperfecta.
Osteogenesis imperfecta is a clinically and genetically heterogeneous group of inherited connective tissue disorders in which bone fragility is the predominant feature. Cultured dermal fibroblasts from one patient with the lethal perinatal form of osteogenesis imperfecta secrete type I procollagen a...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1981
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320349/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6946461/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.8.5142 |
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