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Adjuvant properties of a biocompatible thermo-responsive polymer of N-isopropylacrylamide in autoimmunity and arthritis

To evaluate the thermo-responsive poly(N-isopropylacrylamide) (PNiPAAm) polymer as an adjuvant, we synthesized PNiPAAm through free radical polymerization and characterized it both in vitro and in vivo. The polymer when mixed with collagen type II (CII) induced antigen-specific autoimmunity and arth...

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Detalhes bibliográficos
Main Authors: Shakya, Akhilesh Kumar, Kumar, Ashok, Nandakumar, Kutty Selva
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203480/
https://ncbi.nlm.nih.gov/pubmed/21543351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0114
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