Vaccine-Induced Cross-Genotype Reactive Neutralizing Antibodies Against Hepatitis C Virus

We detected cross-reactive neutralizing antibodies (NtAb) against hepatitis C virus (HCV) in chimpanzees vaccinated with HCV-1 (genotype 1a) recombinant E1/E2 envelope glycoproteins. Five vaccinated chimpanzees, protected following HCV-1 challenge, were initially studied using the heterologous H77 (...

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Main Authors: Meunier, Jean-Christophe, Gottwein, Judith M., Houghton, Michael, Russell, Rodney S., Emerson, Suzanne U., Bukh, Jens, Purcell, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2011
Assuntos:
Major Articles and Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203383/
https://ncbi.nlm.nih.gov/pubmed/21917891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir511
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