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Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso

BACKGROUND: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs may influence the disease risk individually (main effects) or behave jointly (epistatic interactions). For the analysis of...

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Detalhes bibliográficos
Main Authors: Yang, Can, Wan, Xiang, Yang, Qiang, Xue, Hong, Yu, Weichuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203332/
https://ncbi.nlm.nih.gov/pubmed/20122189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-S1-S18
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