Hemoglobin S and C Heterozygosity Enhances Neither the Magnitude nor Breadth of Antibody Responses to a Diverse Array of Plasmodium falciparum Antigens

(See the editorial commentary by Williams, on pages 1651–3.) Background. Heterozygous states of hemoglobin (Hb) A and HbS (HbAS, sickle-cell trait) or HbC (HbAC) protect against Plasmodium falciparum malaria by unclear mechanisms. Several studies suggest that HbAS and HbAC accelerate the acquisition...

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Autors principals: Tan, Xiaolin, Traore, Boubacar, Kayentao, Kassoum, Ongoiba, Aissata, Doumbo, Safiatou, Waisberg, Michael, Doumbo, Ogobara K., Felgner, Philip L., Fairhurst, Rick M., Crompton, Peter D.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203232/
https://ncbi.nlm.nih.gov/pubmed/21998476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jir638
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