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Herpesvirus Telomerase RNA (vTR) with a Mutated Template Sequence Abrogates Herpesvirus-Induced Lymphomagenesis

Telomerase reverse transcriptase (TERT) and telomerase RNA (TR) represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation...

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Autors principals: Kaufer, Benedikt B., Arndt, Sina, Trapp, Sascha, Osterrieder, Nikolaus, Jarosinski, Keith W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203187/
https://ncbi.nlm.nih.gov/pubmed/22046133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002333
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