Herpesvirus Telomerase RNA (vTR) with a Mutated Template Sequence Abrogates Herpesvirus-Induced Lymphomagenesis

Telomerase reverse transcriptase (TERT) and telomerase RNA (TR) represent the enzymatically active components of telomerase. In the complex, TR provides the template for the addition of telomeric repeats to telomeres, a protective structure at the end of linear chromosomes. Human TR with a mutation...

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Autores principales: Kaufer, Benedikt B., Arndt, Sina, Trapp, Sascha, Osterrieder, Nikolaus, Jarosinski, Keith W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203187/
https://ncbi.nlm.nih.gov/pubmed/22046133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002333
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