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Elucidation of the ATP7B N-Domain Mg(2+)-ATP Coordination Site and Its Allosteric Regulation

The diagnostic of orphan genetic disease is often a puzzling task as less attention is paid to the elucidation of the pathophysiology of these rare disorders at the molecular level. We present here a multidisciplinary approach using molecular modeling tools and surface plasmonic resonance to study t...

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Autori principali: Hercend, Claude, Bauvais, Cyril, Bollot, Guillaume, Delacotte, Nicolas, Chappuis, Philippe, Woimant, France, Launay, Jean-Marie, Manivet, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3203118/
https://ncbi.nlm.nih.gov/pubmed/22046264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026245
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