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Mechanical Loading of Articular Cartilage Reduces IL-1-Induced Enzyme Expression
OBJECTIVE: Exposure of articular cartilage to interleukin-1 (IL-1) results in increased synthesis of matrix degrading enzymes. Previously mechanical load applied together with IL-1 stimulation was found to reduce aggrecan cleavage by ADAMTS-4 and 5 and MMP-1, -3, -9, and -13 and reduce proteoglycan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE Publications
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3203026/ https://ncbi.nlm.nih.gov/pubmed/22039566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947603511407484 |
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