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An In Vitro Model for the Pathological Degradation of Articular Cartilage in Osteoarthritis
The objective of this study was to develop an in vitro cartilage degradation model that emulates the damage seen in early-stage osteoarthritis. To this end, cartilage explants were collagenase-treated to induce enzymatic degradation of collagen fibers and proteoglycans at the articular surface. To a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938093/ https://ncbi.nlm.nih.gov/pubmed/24360770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbiomech.2013.11.050 |
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