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Deficiency of SR-BI Leads to Impaired Lymphocyte Homeostasis and Autoimmune Disorders in Mice
OBJECTIVE: Scavenger receptor BI (SR-BI) is an HDL receptor. Recent studies revealed that SR-BI protects against sepsis via modulating innate immunity. However, its role in adaptive immunity is unclear. METHODS AND RESULTS: SR-BI null mice exhibited impaired lymphocyte homeostasis as shown by spleno...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202973/ https://ncbi.nlm.nih.gov/pubmed/21836069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.111.234716 |
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