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Expression of the J chain gene during B cell differentiation is inversely correlated with DNA methylation.

During B cell differentiation, transcription of the J chain gene is initiated. To determine the regulatory mechanism involved, we have analyzed the structure of the J chain gene in cell lines representing successive stages in B cell development. Comparison of restriction sites showed that the J chai...

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Dettagli Bibliografici
Autori principali: Yagi, M, Koshland, M E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1981
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC320291/
https://ncbi.nlm.nih.gov/pubmed/6795624
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