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Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species

BACKGROUND: DNA methylation is one of the main epigenetic mechanisms for the regulation of gene expression in eukaryotes. In the standard model, methylation in gene promoters has received the most attention since it is generally associated with transcriptional silencing. Nevertheless, recent studies...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Epigenetics Chromatin
Hauptverfasser: Anastasiadi, Dafni, Esteve-Codina, Anna, Piferrer, Francesc
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6025724/
https://ncbi.nlm.nih.gov/pubmed/29958539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0205-1
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