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Alpha-Latrotoxin Rescues SNAP-25 from BoNT/A-Mediated Proteolysis in Embryonic Stem Cell-Derived Neurons

The botulinum neurotoxins (BoNTs) exhibit zinc-dependent proteolytic activity against members of the core synaptic membrane fusion complex, preventing neurotransmitter release and resulting in neuromuscular paralysis. No pharmacologic therapies have been identified that clinically relieve botulinum...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mesngon, Mariano, McNutt, Patrick
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202834/
https://ncbi.nlm.nih.gov/pubmed/22069721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins3050489
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