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The Biology of the Cytolethal Distending Toxins

The cytolethal distending toxins (CDTs), produced by a variety of Gram-negative pathogenic bacteria, are the first bacterial genotoxins described, since they cause DNA damage in the target cells. CDT is an A-B(2) toxin, where the CdtA and CdtC subunits are required to mediate the binding on the surf...

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Autori principali: Guerra, Lina, Cortes-Bratti, Ximena, Guidi, Riccardo, Frisan, Teresa
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202825/
https://ncbi.nlm.nih.gov/pubmed/22069704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins3030172
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