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Mitochondria biogenesis and the development of diabetic retinopathy
Retinal mitochondria become dysfunctional and their DNA (mtDNA) is damaged in diabetes. Biogenesis of mitochondria DNA is tightly controlled by nuclear-mitochondrial transcriptional factors, and translocation of transcription factor A (TFAM) to the mitochondria is essential for transcription and rep...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202722/ https://ncbi.nlm.nih.gov/pubmed/21911054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2011.08.017 |
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