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Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development
Cardiac valves originate from endocardial cushions (EC) formed by endothelial-to-mesenchymal transformation (EMT) during embryogenesis. The zinc-finger transcription factor Snai1 has previously been reported to be important for EMT during organogenesis, yet its role in early valve development has no...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202673/ https://ncbi.nlm.nih.gov/pubmed/21920357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.08.022 |
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