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β-Catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse
During heart development endocardial cells within the atrio-ventricular (AV) region undergo TGFβ-dependent epithelial-mesenchymal transformation (EMT) and invade the underlying cardiac jelly. This process gives rise to the endocardial cushions from which AV valves and part of the septum originate. I...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2172268/ https://ncbi.nlm.nih.gov/pubmed/15289495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403050 |
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