β-Catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse

During heart development endocardial cells within the atrio-ventricular (AV) region undergo TGFβ-dependent epithelial-mesenchymal transformation (EMT) and invade the underlying cardiac jelly. This process gives rise to the endocardial cushions from which AV valves and part of the septum originate. I...

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Main Authors: Liebner, Stefan, Cattelino, Anna, Gallini, Radiosa, Rudini, Noemi, Iurlaro, Monica, Piccolo, Stefano, Dejana, Elisabetta
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2004
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Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172268/
https://ncbi.nlm.nih.gov/pubmed/15289495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200403050
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