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Quantification of repolarization reserve to understand inter-patient variability in the response to pro-arrhythmic drugs: a computational analysis
BACKGROUND: "Repolarization reserve" is frequently invoked to explain why potentially pro-arrhythmic drugs cause, across a population, a range of changes to cardiac action potentials (APs). The mechanisms underlying this inter-individual variability, however, are not understood quantitativ...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202650/ https://ncbi.nlm.nih.gov/pubmed/21699863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2011.05.023 |
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