Reversal of Fragile X Phenotypes by Manipulation of AβPP/Aβ Levels in Fmr1(KO) Mice

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and the leading known genetic cause of autism. Fragile X mental retardation protein (FMRP), which is absent or expressed at substantially reduced levels in FXS, binds to and controls the postsynaptic translation of...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Westmark, Cara J., Westmark, Pamela R., O'Riordan, Kenneth J., Ray, Brian C., Hervey, Crystal M., Salamat, M. Shahriar, Abozeid, Sara H., Stein, Kelsey M., Stodola, Levi A., Tranfaglia, Michael, Burger, Corinna, Berry-Kravis, Elizabeth M., Malter, James S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2011
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202540/
https://ncbi.nlm.nih.gov/pubmed/22046307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026549
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