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Pin1 and PKMζ Sequentially Control Dendritic Protein Synthesis
Some forms of learning and memory, and their electrophysiologic correlate, long-term potentiation (LTP), require dendritic translation. We demonstrate that Pin1, a peptidyl-prolyl isomerase, is present in dendritic spines and shafts and inhibits protein synthesis induced by glutamatergic signaling....
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972507/ https://ncbi.nlm.nih.gov/pubmed/20215645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000451 |
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