Elevated Stearoyl-CoA Desaturase in Brains of Patients with Alzheimer's Disease

The molecular bases of Alzheimer's disease (AD) remain unclear. We used a lipidomic approach to identify lipid abnormalities in the brains of subjects with AD (N = 37) compared to age-matched controls (N = 17). The analyses revealed statistically detectable elevations in levels of non-esterifie...

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Main Authors: Astarita, Giuseppe, Jung, Kwang-Mook, Vasilevko, Vitaly, DiPatrizio, Nicholas V., Martin, Sarah K., Cribbs, David H., Head, Elizabeth, Cotman, Carl W., Piomelli, Daniele
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202527/
https://ncbi.nlm.nih.gov/pubmed/22046234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024777
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