Deficient Liver Biosynthesis of Docosahexaenoic Acid Correlates with Cognitive Impairment in Alzheimer's Disease

Reduced brain levels of docosahexaenoic acid (C22:6n-3), a neurotrophic and neuroprotective fatty acid, may contribute to cognitive decline in Alzheimer's disease. Here, we investigated whether the liver enzyme system that provides docosahexaenoic acid to the brain is dysfunctional in this dise...

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Huvudupphovsmän: Astarita, Giuseppe, Jung, Kwang-Mook, Berchtold, Nicole C., Nguyen, Vinh Q., Gillen, Daniel L., Head, Elizabeth, Cotman, Carl W., Piomelli, Daniele
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2935886/
https://ncbi.nlm.nih.gov/pubmed/20838618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012538
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