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Resolving TRPV1- and TNF-α-Mediated Spinal Cord Synaptic Plasticity and Inflammatory Pain with Neuroprotectin D1

Mechanisms of inflammatory pain are not fully understood. We investigated the role of TRPV1 (transient receptor potential subtype V1) and TNF-α, two critical mediators for inflammatory pain, in regulating spinal cord synaptic transmission. We found in mice lacking Trpv1 the frequency but not the amp...

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Главные авторы: Park, Chul-Kyu, Lü, Ning, Xu, Zhen-Zhong, Liu, Tong, Serhan, Charles N., Ji, Ru-Rong
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202339/
https://ncbi.nlm.nih.gov/pubmed/22016541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2443-11.2011
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