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Characterization of complex chromosomal rearrangements by targeted capture and next-generation sequencing

Translocations are a common class of chromosomal aberrations and can cause disease by physically disrupting genes or altering their regulatory environment. Some translocations, apparently balanced at the microscopic level, include deletions, duplications, insertions, or inversions at the molecular l...

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Detalhes bibliográficos
Main Authors: Sobreira, Nara L.M., Gnanakkan, Veena, Walsh, Michael, Marosy, Beth, Wohler, Elizabeth, Thomas, George, Hoover-Fong, Julie E., Hamosh, Ada, Wheelan, Sarah J., Valle, David
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202288/
https://ncbi.nlm.nih.gov/pubmed/21890680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122986.111
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