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DNA methylation profiles of human active and inactive X chromosomes
X-chromosome inactivation (XCI) is a dosage compensation mechanism that silences the majority of genes on one X chromosome in each female cell. To characterize epigenetic changes that accompany this process, we measured DNA methylation levels in 45,X patients carrying a single active X chromosome (X...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202277/ https://ncbi.nlm.nih.gov/pubmed/21862626 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.112680.110 |
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