DNA methylation profiles of human active and inactive X chromosomes

X-chromosome inactivation (XCI) is a dosage compensation mechanism that silences the majority of genes on one X chromosome in each female cell. To characterize epigenetic changes that accompany this process, we measured DNA methylation levels in 45,X patients carrying a single active X chromosome (X...

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Detalles Bibliográficos
Main Authors: Sharp, Andrew J., Stathaki, Elisavet, Migliavacca, Eugenia, Brahmachary, Manisha, Montgomery, Stephen B., Dupre, Yann, Antonarakis, Stylianos E.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2011
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202277/
https://ncbi.nlm.nih.gov/pubmed/21862626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.112680.110
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