Analysis of alternative splicing associated with aging and neurodegeneration in the human brain

Age is the most important risk factor for neurodegeneration; however, the effects of aging and neurodegeneration on gene expression in the human brain have most often been studied separately. Here, we analyzed changes in transcript levels and alternative splicing in the temporal cortex of individual...

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Main Authors: Tollervey, James R., Wang, Zhen, Hortobágyi, Tibor, Witten, Joshua T., Zarnack, Kathi, Kayikci, Melis, Clark, Tyson A., Schweitzer, Anthony C., Rot, Gregor, Curk, Tomaž, Zupan, Blaž, Rogelj, Boris, Shaw, Christopher E., Ule, Jernej
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202275/
https://ncbi.nlm.nih.gov/pubmed/21846794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122226.111
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