Analysis of alternative splicing associated with aging and neurodegeneration in the human brain

Age is the most important risk factor for neurodegeneration; however, the effects of aging and neurodegeneration on gene expression in the human brain have most often been studied separately. Here, we analyzed changes in transcript levels and alternative splicing in the temporal cortex of individual...

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Autori principali: Tollervey, James R., Wang, Zhen, Hortobágyi, Tibor, Witten, Joshua T., Zarnack, Kathi, Kayikci, Melis, Clark, Tyson A., Schweitzer, Anthony C., Rot, Gregor, Curk, Tomaž, Zupan, Blaž, Rogelj, Boris, Shaw, Christopher E., Ule, Jernej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202275/
https://ncbi.nlm.nih.gov/pubmed/21846794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.122226.111
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