The Cellular Prion Protein Prevents Copper-Induced Inhibition of P2X(4) Receptors

Although the physiological function of the cellular prion protein (PrP(C)) remains unknown, several evidences support the notion of its role in copper homeostasis. PrP(C) binds Cu(2+) through a domain composed by four to five repeats of eight amino acids. Previously, we have shown that the perfusion...

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Main Authors: Lorca, Ramón A., Varela-Nallar, Lorena, Inestrosa, Nibaldo C., Huidobro-Toro, J. Pablo
Format: Artigo
Sprog:Inglês
Udgivet: SAGE-Hindawi Access to Research 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202100/
https://ncbi.nlm.nih.gov/pubmed/22114745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/706576
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