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Inhibition of PKCβ Reverses Increased Blood-brain Barrier Permeability during Hyperglycemic Stroke and Prevents Edema Formation In Vivo

PURPOSE: We investigated the effect of circulating factors and protein kinase Cβ (PKCβ) on blood-brain barrier permeability and edema during hyperglycemic stroke. METHODS: Male Wistar rats that were hyperglycemic by streptozotocin (50 mg/kg) for 5–6 days underwent middle cerebral artery occlusion (M...

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書誌詳細
主要な著者: Cipolla, Marilyn J., Huang, Quillan, Sweet, Julie G.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202059/
https://ncbi.nlm.nih.gov/pubmed/21852606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.623991
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