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Inhibition of PKCβ Reverses Increased Blood-brain Barrier Permeability during Hyperglycemic Stroke and Prevents Edema Formation In Vivo
PURPOSE: We investigated the effect of circulating factors and protein kinase Cβ (PKCβ) on blood-brain barrier permeability and edema during hyperglycemic stroke. METHODS: Male Wistar rats that were hyperglycemic by streptozotocin (50 mg/kg) for 5–6 days underwent middle cerebral artery occlusion (M...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202059/ https://ncbi.nlm.nih.gov/pubmed/21852606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.111.623991 |
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