Analysis of nucleic acid chaperoning by the prion protein and its inhibition by oligonucleotides

Prion diseases are unique neurodegenerative illnesses associated with the conversion of the cellular prion protein (PrP(C)) into the aggregated misfolded scrapie isoform, named PrP(Sc). Recent studies on the physiological role of PrP(C) revealed that this protein has probably multiple functions, not...

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Bibliographic Details
Main Authors: Guichard, Cécile, Ivanyi-Nagy, Roland, Sharma, Kamal Kant, Gabus, Caroline, Marc, Daniel, Mély, Yves, Darlix, Jean-Luc
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201874/
https://ncbi.nlm.nih.gov/pubmed/21737432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr554
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