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Analysis of nucleic acid chaperoning by the prion protein and its inhibition by oligonucleotides

Prion diseases are unique neurodegenerative illnesses associated with the conversion of the cellular prion protein (PrP(C)) into the aggregated misfolded scrapie isoform, named PrP(Sc). Recent studies on the physiological role of PrP(C) revealed that this protein has probably multiple functions, not...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Guichard, Cécile, Ivanyi-Nagy, Roland, Sharma, Kamal Kant, Gabus, Caroline, Marc, Daniel, Mély, Yves, Darlix, Jean-Luc
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2011
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201874/
https://ncbi.nlm.nih.gov/pubmed/21737432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr554
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