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Analysis of nucleic acid chaperoning by the prion protein and its inhibition by oligonucleotides
Prion diseases are unique neurodegenerative illnesses associated with the conversion of the cellular prion protein (PrP(C)) into the aggregated misfolded scrapie isoform, named PrP(Sc). Recent studies on the physiological role of PrP(C) revealed that this protein has probably multiple functions, not...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201874/ https://ncbi.nlm.nih.gov/pubmed/21737432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr554 |
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