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The SLP-76 SH2 domain is required for T cell development and activation

The adaptor protein Src homology 2 (SH2) domain containing leukocyte protein of 76 kDa (SLP-76) is critical for multiple aspects of T cell development and function. Through its protein-binding domains, SLP-76 serves as a platform for the assembly of multiple enzymes and adaptor proteins that functio...

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Main Authors: Burns, Jeremy C., Corbo, Evann, Degen, Janine, Gohil, Mercy, Anterasian, Christine, Schraven, Burkart, Koretzky, Gary A., Kliche, Stefanie, Jordan, Martha S.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201803/
https://ncbi.nlm.nih.gov/pubmed/21949020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903379
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