Synthesis and biophysical studies of short oligodeoxynucleotides with novel modifications: a possible approach to the problem of mixed base oligodeoxynucleotide synthesis.

The syntheses of 1,2-dideoxy-D-ribofuranose and 1,2-dideoxy-1-phenyl-beta-D-ribofuranose are described. Oligodeoxynucleotides containing these analogues have been synthesised and hybridized to their complementary strands. Hypochromicity studies have shown that these duplices are less stable than eit...

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Autors principals: Millican, T A, Mock, G A, Chauncey, M A, Patel, T P, Eaton, M A, Gunning, J, Cutbush, S D, Neidle, S, Mann, J
Format: Artigo
Idioma:Inglês
Publicat: 1984
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC320173/
https://ncbi.nlm.nih.gov/pubmed/6548562
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