Preclinical Study of Treatment Response in HCT-116 Cells and Xenografts with (1)H-decoupled (31)P MRS

The topoisomerase I inhibitor, irinotecan, and its active metabolite SN-38 have been shown to induce G(2)/M cell cycle arrest without significant cell death in human colon carcinoma cells (HCT-116). Subsequent treatment of these G(2)/M-arrested cells with the cyclin-dependent kinase inhibitor, flavo...

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Detalhes bibliográficos
Main Authors: Darpolor, Moses M., Kennealey, Peter T., Carl Le, H, Zakian, Kristen L., Ackerstaff, Ellen, Rizwan, Asif, Chen, Jin-Hong, Sambol, Elliot B., Schwartz, Gary K., Singer, Samuel, Koutcher, Jason A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201722/
https://ncbi.nlm.nih.gov/pubmed/21994185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.1674
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