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A Data Driven Method for Identifying Rare Variants with Heterogeneous Trait Effects
Collapsing multiple variants into one variable and testing their collective effect is a useful strategy for rare variant association analysis. Direct collapsing, however, is not valid or may significantly lose power when a group of variants to be collapsed have heterogeneous effects on target traits...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201701/ https://ncbi.nlm.nih.gov/pubmed/21818776 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20618 |
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