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Oligonucleotide directed mutagenesis of Escherichia coli 5S ribosomal RNA: construction of mutant and structural analysis.

The ribosomal 5S RNA gene from the rrnB operon of E. coli was mutagenised in vitro using a synthetic oligonucleotide hybridised to M13 ssDNA containing that gene. The oligonucleotide corresponded to the 5S RNA sequence positions 34 to 51 and changed the guanosine at position 41 to a cytidine. The DN...

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Autors principals: Göringer, H U, Wagner, R, Jacob, W F, Dahlberg, A E, Zwieb, C
Format: Artigo
Idioma:Inglês
Publicat: 1984
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC320134/
https://ncbi.nlm.nih.gov/pubmed/6091046
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