A live-attenuated chlamydial vaccine protects against trachoma in nonhuman primates

Blinding trachoma is an ancient neglected tropical disease caused by Chlamydia trachomatis for which a vaccine is needed. We describe a live-attenuated vaccine that is safe and efficacious in preventing trachoma in nonhuman primates, a model with excellent predictive value for humans. Cynomolgus mac...

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Detalhes bibliográficos
Main Authors: Kari, Laszlo, Whitmire, William M., Olivares-Zavaleta, Norma, Goheen, Morgan M., Taylor, Lacey D., Carlson, John H., Sturdevant, Gail L., Lu, Chunxue, Bakios, Lauren E., Randall, Linnell B., Parnell, Michael J., Zhong, Guangming, Caldwell, Harlan D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201208/
https://ncbi.nlm.nih.gov/pubmed/21987657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20111266
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