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Immunization with the attenuated plasmidless Chlamydia trachomatis L2(25667R) strain provides partial protection in a murine model of female genitourinary tract infection
Here we report on the safety, immunogenicity, and vaccine efficacy of the naturally occurring plasmid-free attenuated Chlamydia trachomatis L2-5667R strain in a murine infection model. Intravaginal Immunization induced both chlamydial specific serum antibody and systemic CD4(+) Th1 biased immune res...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821993/ https://ncbi.nlm.nih.gov/pubmed/20004265 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.11.073 |
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