Immunization with the attenuated plasmidless Chlamydia trachomatis L2(25667R) strain provides partial protection in a murine model of female genitourinary tract infection

Here we report on the safety, immunogenicity, and vaccine efficacy of the naturally occurring plasmid-free attenuated Chlamydia trachomatis L2-5667R strain in a murine infection model. Intravaginal Immunization induced both chlamydial specific serum antibody and systemic CD4(+) Th1 biased immune res...

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Autores principales: Olivares-Zavaleta, Norma, Whitmire, William, Gardner, Donald, Caldwell, Harlan D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821993/
https://ncbi.nlm.nih.gov/pubmed/20004265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.11.073
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