Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria

The role of the IgE–FcεRI complex in malaria severity in Plasmodium falciparum–hosting patients is unknown. We demonstrate that mice genetically deficient for the high-affinity receptor for IgE (FcεRIα-KO) or for IgE (IgE-KO) are less susceptible to experimental cerebral malaria (ECM) after infectio...

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Main Authors: Porcherie, Adeline, Mathieu, Cedric, Peronet, Roger, Schneider, Elke, Claver, Julien, Commere, Pierre-Henri, Kiefer-Biasizzo, Hélène, Karasuyama, Hajime, Milon, Geneviève, Dy, Michel, Kinet, Jean-Pierre, Louis, Jacques, Blank, Ulrich, Mécheri, Salaheddine
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201201/
https://ncbi.nlm.nih.gov/pubmed/21967768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110845
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