Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria

The role of the IgE–FcεRI complex in malaria severity in Plasmodium falciparum–hosting patients is unknown. We demonstrate that mice genetically deficient for the high-affinity receptor for IgE (FcεRIα-KO) or for IgE (IgE-KO) are less susceptible to experimental cerebral malaria (ECM) after infectio...

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Autors principals: Porcherie, Adeline, Mathieu, Cedric, Peronet, Roger, Schneider, Elke, Claver, Julien, Commere, Pierre-Henri, Kiefer-Biasizzo, Hélène, Karasuyama, Hajime, Milon, Geneviève, Dy, Michel, Kinet, Jean-Pierre, Louis, Jacques, Blank, Ulrich, Mécheri, Salaheddine
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2011
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201201/
https://ncbi.nlm.nih.gov/pubmed/21967768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110845
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