An Integrin α4β7•IgG Heterodimeric Chimera Binds to MAdCAM-1 on High Endothelial Venules in Gut-Associated Lymphoid Tissue

Lymphocyte homing is regulated by a multistep process mediated by sequential adhesive interactions between circulating lymphocytes and high endothelial venules (HEVs). In gut-associated lymphoid tissue (GALT), the initial interactive step, “tethering and rolling,” is partly mediated by integrin α4β7...

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Autores principales: Hoshino, Hitomi, Kobayashi, Motohiro, Mitoma, Junya, Sato, Yoshiko, Fukuda, Minoru, Nakayama, Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201193/
https://ncbi.nlm.nih.gov/pubmed/21430257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155411404416
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