Development of Mucosal PNAd(+) and MAdCAM-1(+) Venules during Disease Course in Ulcerative Colitis

PNAd and MAdCAM-1 addressins on venules are of importance in T-cell homing and potential therapeutic targets in ulcerative colitis (UC). Normally, PNAd(+) high endothelial venules (HEVs) are only present in lymphoid organs, whereas small numbers of MAdCAM-1(+) venules can be seen in non-lymphoid tis...

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Gepubliceerd in:Cells
Hoofdauteurs: Roosenboom, Britt, van Lochem, Ellen G., Meijer, Jos, Smids, Carolijn, Nierkens, Stefan, Brand, Eelco C., van Erp, Liselot W., Kemperman, Larissa G.J.M., Groenen, Marcel J.M., Horjus Talabur Horje, Carmen S., Wahab, Peter J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226824/
https://ncbi.nlm.nih.gov/pubmed/32268498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9040891
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