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Cell surface thiol isomerases may explain the platelet-selective action of S-nitrosoglutathione

S-nitrosoglutathione (GSNO) at low concentration inhibits platelet aggregation without causing vasodilation, suggesting platelet-selective nitric oxide delivery. The mechanism of this selectivity is unknown, but may involve cell surface thiol isomerases, in particular protein disulphide isomerase (c...

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Bibliographic Details
Main Authors: Xiao, Fang, Gordge, Michael P.
Format: Artigo
Language:Inglês
Published: Academic Press 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200429/
https://ncbi.nlm.nih.gov/pubmed/21642008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2011.05.008
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